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Educational Session

Biotherapies, Cellular Therapies, and Immunotherapies

AM25-SN-13-L - Update on the Use of Cryopreserved Platelets in Acute Surgical Settings

Sunday, October 26, 2025
2:30 PM - 3:30 PM  PT
Room: SDCC 20D

    Speaker(s)

  • Jose Cancelas (he/him/his)

    Executive Director, Connell and O'Reilly Families Cell Manipulation Core Facility, Medical Oncology
    Dana-Farber Cancer Institute
    Boston, Massachusetts

    Disclosure(s): Cellphire: Consultant/Advisory Board (Ongoing); Fresenius Kabi: Consultant/Advisory Board (Ongoing); GDIT: Grant reviewer (Terminated, July 17, 2025); Hemanext: Consultant/Advisory Board (Terminated, July 17, 2025); Hemerus LLC: Consultant/Advisory Board (Ongoing); NIH: Grant reviewer (Ongoing); PLATEFUSE: Stock Shareholder (self-managed) (Ongoing); PRESERVATION BIO: Consultant/Advisory Board (Ongoing), Stock Shareholder (self-managed) (Ongoing); Rion LLC: Consultant/Advisory Board (Ongoing); Teleflex: Consultant/Advisory Board (Ongoing); TerumoBCT: Consultant/Advisory Board (Ongoing); Velico Medical: Consultant/Advisory Board (Ongoing); Westat Inc: Grant/Research Support (Ongoing); X4: Consultant/Advisory Board (Ongoing)

  • Glenn Whitman, MD (he/him/his)

    Professor, Division of Cardiac Surgery, Co-Director, CVSICU, JHH Director, Cardiac Surgery Quality,JHHS
    Johns Hopkins School of Medicine
    Baltimore, Maryland

    Disclosure(s): Cellphire THerapeutics Inc.: Consultant/Advisory Board (Ongoing); GWBN LLC: Full-time/Part-time Employee or Owner (Ongoing)

    • Program Chair(s)

  • Claudia Cohn, MD, PhD (she/her/hers)

    Professor of Laboratory Medicine and Pathology, Director, Blood Bank Laboratory
    University of Minnesota
    Minneapolis, Minnesota

    Disclosure(s): AABB: Consultant/Advisory Board (Ongoing); Fresenius Kabi: Consultant/Advisory Board (Ongoing); ICCBBA: Board of DIrectors (Ongoing)

    • Speaker(s)

  • Claudia Cohn, MD, PhD (she/her/hers)

    Professor of Laboratory Medicine and Pathology, Director, Blood Bank Laboratory
    University of Minnesota
    Minneapolis, Minnesota

    Disclosure(s): AABB: Consultant/Advisory Board (Ongoing); Fresenius Kabi: Consultant/Advisory Board (Ongoing); ICCBBA: Board of DIrectors (Ongoing)

This session will provide an update on the “Use of Cryopreserved Platelets in Acute Surgical Settings”. To provide context for this session, the first speaker will present an update on the basic science of platelet products used clinically including differences in manufacturing approaches and resulting product characteristics of cryopreserved platelets versus room temperature and cold stored platelets. The next speaker will present key results from a recently conducted Systematic Literature Review that will provide the audience with a evidence-based summary of outcome data relating to the clinical use of cryopreserved platelets in acute surgical settings with comparison to cold stored and room temperature platelets. Finally, the last speaker will present topline results from the CRYPTICS - NCT04709705 Phase 2/3 clinical trial supporting the first cryopreserved platelet product being developed for approved use in the US.

Learning Objectives:

  • Describe differences in the way cryopreserved platelets are manufactured, compare the resultant properties to liquid stored platelets and interpret the significance of these differences
  • Summarize key findings from the most recent findings of a Systematic Literature Review on the use of cryopreserved platelets in acute surgical bleeding settings
  • Review the topline results from the Phase 2/3 CRYPTICS clinical trial and report the key take-aways