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Jose Cancelas, MD, PhD

Executive Director, Connell and O'Reilly Families Cell Manipulation Core Facility, Medical Oncology
Dana-Farber Cancer Institute
Boston, Massachusetts

Jose Cancelas is a hematologist with a broad background in transfusion medicine, cell therapies, hematology, and stem cell biology. He is the executive director of the Connell and O’Reilly Cell Manipulations Core Facility at Dana Farber Cancer Institute, Harvard Medical School, in Boston, Massachusetts, where he is responsible for managing a research portfolio on translational and clinical studies involving hemotherapies, stem cell therapies and immune-effector therapies for the treatment of a spectrum of diseases that benefit or may benefit from the application of modified blood derived therapeutics.
His research program is diverse and has resulted in over 220 peer-reviewed manuscripts published in high-impact factor journals, and of course, in Transfusion where he is one of the Associate Editors. As a researcher, he leads a Federal Government funded group that focus on translational application of diverse hemotherapies. His translational group has optimized methods of progenitor and granulocyte transfusion in neutropenic patients and validated novel methods to preserve and store platelets, red cells and T cells in clinical multi-center trials. His group has generated first-in-human clinical data for a variety of biological therapies and is now actively searching for the mechanisms that control cold platelet damage and identified key molecular signals and methods to prevent cold storage damage and produce cryopreserved and lyophilized platelets.

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