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AM25-MN-37-L - AABB’s Updated Platelet and Red Blood Cell Transfusion Guidelines

Monday, October 27, 2025
10:00 AM - 11:30 AM  PT
Location: 30CDE

    Program Chair(s)

  • Claudia Cohn, MD, PhD (she/her/hers)

    Professor of Laboratory Medicine and Pathology, Director, Blood Bank Laboratory
    University of Minnesota
    Minneapolis, Minnesota

    Disclosure information not submitted.

  • Aaron A.R Tobian, MD, PhD

    Professor
    Johns Hopkins University
    Baltimore, Maryland

    Disclosure information not submitted.

    • Speaker(s)

  • Simon J. Stanworth, FRCP FRCPath DPhil

    Professor of Haematology and Transfusion Medicine; Consultant Haematologist
    University Oxford
    Oxford, England

    Disclosure(s): No financial relationships to disclose

  • Monica B. Pagano, MD (she/her/hers)

    Professor of Laboratory Medicine and Pathology, Division Head Transfusion Medicine
    University of Washington Medical Center
    Seattle, Washington

    Disclosure(s): No financial relationships to disclose

  • RM

    Ryan A. Metcalf, MD

    Section Chief, Transfusion Medicine
    University of Utah Health
    Salt Lake City, Utah

    Disclosure information not submitted.

With the growing body of evidence from randomized controlled trials, AABB updated platelet (PLT) and red blood cell (RBC) transfusion guidelines to better inform clinical decisions. These new recommendations offer practical guidance for clinical use of platelets and red cells in selected populations. This interactive educational session will use real-world case discussions to provide an understanding of updated recommendations, highlight areas of uncertainty where quality of evidence is lower, and explore practical strategies for implementation in various clinical settings.

Learning Objectives:

  • Describe the guidelines and present the up-to-date recommendations for platelet and red blood cell transfusions
  • Consider less commonly discussed key concepts in evidence-based medicine and how they led to a rationale for guidance
  • Explore the challenges of applying strong and conditional recommendations  using real-case scenarios