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Blood Center/Hospital-Based Donor Center - Donor Testing

(P-BC-37) Evaluation of Non-invasive Hemoglobin Measurement in Blood Donors at Tertiary Care Hospital, Bangkok, Thailand.

Sunday, October 26, 2025
12:00 PM - 1:00 PM  PT
Background/Case Studies: Hemoglobin (Hb) assessment is an important tool to prevent blood collection from an anemic donor. Currently hemoglobin measurement can be done without a finger prick. This study aimed to evaluate the non-invasive fingertip Hb measurement of blood donors compared with the venous blood hemoglobin measurement by an automated blood analyzer.

Study

Design/Methods: This study was approved by institute review board COA no. Si 606/2024. We consented and recruited blood donors who qualified based-on a health history interview and basic physical examination. The Hb level was measured from each participant fingertip by non-invasive device (Rad-67 Pulse CO-Oximeter; HbRAD-67), followed by a venous blood hemoglobin measurement by automated hematology analyzer (Sysmex XN 550; HbCBC). The correlation and concordance between the non-invasive hemoglobin measurements were analyzed using an Intraclass Correlation Coefficient (ICC) and a Bland-Altman agreement plot, while the satisfaction between non-invasive device and standard device was evaluated using Likert scale.

Results/Findings: There were 169 male and 126 female participants. The average of HbRAD-67 and HbCBC levels were 14.38±1.12 g/dL and 13.90±1.16 g/dL, respectively. The ICC outcome was 0.6 (95% CI: 0.52-0.67). Considering result of hemoglobin measurement for pre-donation screening, non-invasive hemoglobin measurement had sensitivity of 98.1% accuracy 88.5%. The satisfaction survey between HbRAD-67 and the routine point-of -care hemoglobin measurement for the speed of test, pain and safety were 96.6% vs 76.3%, 99.0 % vs 47.5% and 98.6% vs 65.4% respectively.

Conclusions: The non-invasive Hb measurement exhibited moderate agreement compared to automated blood analyzer. The satisfaction on Hb assessment with the new non-invasive were higher than invasive routine hemoglobin measurement.